Supplement Architecture

How the NIMARSTI™ Health Architecture Is Implemented in the Real World

The NIMARSTI™ Supplement Architecture translates biological structure into carefully governed, real-world implementations.

Rather than offering isolated products or consumer-driven stacks, NIMARSTI™ develops supplementation as a coordinated biological system—designed to support regulation, resilience, and long-term safety across the lifespan.

Each formulation is positioned within a defined architectural layer. Products are designed to work in relationship, not competition, and are introduced only when their role within the system is clear, necessary, and evidence-supported.

This page presents the full supplement architecture as a system, including formulations in active development and those planned for staged manufacturing. It is intended to communicate design intent, coherence, and long-term vision, not to function as a retail catalog.

A Note on Development Status

NIMARSTI™ follows a deliberate, phased manufacturing strategy.

Formulations are developed, validated, and produced sequentially—beginning with foundational systems that establish tolerance, integration, and safety before expanding into higher-order support.

At present:

MicroBiomeKETO™ is the first formulation moving toward manufacturing
Additional formulations shown below represent architecturally complete designs scheduled for future production phases
No formulation is released until its upstream dependencies are validated and its role within the system is non-redundant

This approach reflects the same governing principle applied throughout the architecture:
structure precedes scale.

How to Read This Architecture

The supplement architecture is organized by biological dependency, not consumer preference.

Each section below represents a functional layer within the system. Higher layers do not compensate for instability in lower ones.

Foundational layers establish biological competence
Integrative layers coordinate tolerance and signaling
Expressive layers support structure, repair, and resilience

Products are listed within the layer they serve.
Detailed formulation data, timelines, and release status are intentionally conservative.

This is supplementation as infrastructure, not escalation.

Architectural Design Commitments

All NIMARSTI™ formulations adhere to the same governing constraints:

Non-redundancy by design — every product has a single, defensible role
Evidence-aligned dosing — grounded in human physiology, not marketing
Lifecycle separation — adult and pediatric systems are never scaled versions of one another
Long-term safety orientation — suitability for sustained use is a prerequisite, not a claim
Modular scalability — products can be introduced or removed without destabilizing the system

This architecture is designed to scale horizontally through coherence, not vertically through proliferation.

🧬 Micronutrient Foundations

Baseline Biological Competence

Micronutrients form the base layer of biological competence within the NIMARSTI™ Health Architecture.

They provide the enzymatic cofactors required for energy production, cellular repair, immune regulation, detoxification, neuroendocrine signaling, and long-term structural integrity. Without sufficient micronutrient availability, higher-order systems cannot regulate, adapt, or recover reliably.

This layer is designed to establish baseline stability, not to force performance or compensate for upstream deficits.

Role in the system
Establishes foundational biochemical sufficiency so that microbiome modulation, detoxification, signaling, and physical adaptation can occur safely and coherently.

Products Within This Layer

NIMARSTI™ AM Multi™

Architectural Role
Morning micronutrient activation supporting metabolic readiness, mitochondrial function, cellular protection, and long-term disease prevention.

Lifecycle Context
Adult physiology.

Development Status
🔒 Formulation complete · OEM-ready · Regulatory-ready · Pilot-ready
Scheduled for manufacturing following initial microbiome system rollout.

NIMARSTI™ PM Minerals™

Architectural Role
Evening mineral repletion supporting parasympathetic regulation, neuromuscular relaxation, tissue repair, and long-term cardiometabolic resilience.

Lifecycle Context
Adult physiology.

Development Status
🔒 Formulation complete · OEM-ready · Regulatory-ready · Pilot-ready
Designed to function in direct architectural symmetry with AM Multi™.

NIMARSTI™ Kids Multi™

Architectural Role
Foundational pediatric micronutrient support designed to meet developmental needs for growth, brain maturation, immune resilience, and nervous system stability without overstimulation.

Lifecycle Context
Pediatric (ages 4–12; adjusted dosing for ages 2–4 under guidance).

Development Status
🔒 Formulation complete · OEM-ready · Regulatory-ready · Pilot-ready Planned for later-stage release following adult system establishment.

Architectural Notes (Investor-Relevant)

These formulations are not interchangeable multis
Adult and pediatric systems are structurally distinct, not scaled versions
AM and PM separation reflects circadian biology, not convenience
Micronutrients are intentionally non-redundant with microbiome and herbal layers

The decision to defer manufacturing of these products until after initial microbiome deployment reflects systems discipline, not product hesitation. Micronutrient foundations are most effective when introduced into a stabilized microbiome and regulatory environment.

Relationship to Other Layers

Micronutrient Foundations form the base layer of the NIMARSTI™ Health Architecture.

Downstream of:
None — this layer establishes foundational biochemical sufficiency.

Upstream of:
🦠 Microbiome Modulation
🌿 Herbal Signaling Systems
⚙️ Developmental & Functional Support
🧠 Omega-3 Essential Fatty Acids

Micronutrient support does not compensate for regulatory dysfunction or environmental overload. It establishes the biochemical conditions required for all higher-order systems to function safely and coherently.

🦠 Microbiome Modulation System

Systems Integration & Tolerance

The microbiome functions as a central systems integrator within the NIMARSTI™ Health Architecture, influencing digestion, immune tone, metabolic signaling, detoxification capacity, and tolerance to other forms of support.

Microbiome stability shapes how all other layers of the architecture are tolerated, interpreted, and expressed over time.

Role in the system
Integrates and modulates inputs across the architecture, shaping downstream response, resilience, and long-term regulatory capacity.

Products Within This Layer

MicroBiomeCORE™

Architectural Role
Advanced daily microbiome nutrition designed to feed, signal, stabilize, and expand gut microbial ecosystems in the general adult population.

Lifecycle Context
Adult physiology (non-ketogenic).

Development Status
🔒 Formulation complete · OEM-ready · Regulatory-ready · Pilot-ready
Planned for future manufacturing following validation of foundational rollout.

MicroBiomeKETO™

Architectural Role
Context-specific microbiome support designed for ketogenic, low-carbohydrate, and fasting-adjacent metabolic states, positioned to stabilize gut ecology without glycemic or insulinemic impact.

Lifecycle Context
Adult physiology (metabolically constrained contexts).

Development Status
🟡 First formulation moving toward manufacturing
Selected as the initial release due to its clearly bounded context, high unmet need, and strong architectural containment.

MicroBiomeKIDS™

Architectural Role
Gentle daily microbiome foundation for children, prioritizing tolerance, stability, and long-term gut–brain support without overstimulation.

Lifecycle Context
Pediatric (ages 4–12; reduced dosing for ages 2–4 under guidance).

Development Status
🔒 Formulation complete · OEM-ready · Regulatory-ready · Pilot-ready
Planned for later-stage release following adult system establishment.

Architectural Notes

These three formulations are not variants of the same product
Each occupies a distinct metabolic and lifecycle context
No formulation competes with or substitutes for another
Together, they define a complete microbiome subsystem that can scale without redundancy

The decision to manufacture MicroBiomeKETO™ first reflects architectural discipline, not prioritization by market size. Its constrained metabolic context allows early validation of tolerance, compliance, and systems integration before broader population rollout.

Relationship to Other Layers

The Microbiome Modulation System operates as an integrative coordination layer within the NIMARSTI™ Health Architecture.

Downstream of:
🧬 Micronutrient Foundations

Upstream of:
🌿 Herbal Signaling Systems
⚙️ Developmental & Functional Support
🧠 Omega-3 Essential Fatty Acids

Microbiome modulation does not replace nutritional sufficiency or override regulatory capacity. It shapes tolerance, signaling fidelity, and downstream responsiveness within an already supported system.

🌿 Herbal Signaling Systems

Regulatory Communication, Not Stimulation

Within the NIMARSTI™ Health Architecture, botanical formulations are used as biological signals, not as stimulants, sedatives, or symptom suppressors.

Herbal systems interact with regulatory pathways—vascular, neuroendocrine, immune, and metabolic—shaping how the body adapts to stress, repair, and aging over time. Their role is to communicate with biology, not override it.

This layer operates downstream of micronutrient sufficiency and microbiome stability, and upstream of structural repair, metabolic resilience, and cognitive aging.

Role in the system
Supports regulatory signaling, stress adaptation, vascular integrity, and long-term resilience through non-stimulatory, evidence-backed botanical communication.

Products Within This Layer

NIMARSTI™ Signal AM™

Architectural Role
Day-phase botanical signaling designed to support cardiometabolic protection, vascular health, cognitive endurance, and anti-aging pathways without stimulant-driven activation.

Lifecycle Context
Adult physiology.

Development Status
🔒 Formulation complete · OEM-ready · Regulatory-ready · Pilot-ready
Designed for lifelong daily use within the morning phase of the architecture.

NIMARSTI™ Restore PM™

Architectural Role
Night-phase botanical signaling designed to support neuroprotection, stress-axis recovery, immune repair, and healthy cognitive aging during parasympathetic dominance.

Lifecycle Context
Adult physiology.

Development Status
🔒 Formulation complete · OEM-ready · Regulatory-ready · Pilot-ready
Designed to complement Signal AM™ without pathway overlap or circadian interference.

Architectural Notes (Investor-Relevant)

AM and PM formulations are not mirrors — they are circadian-specific by design
No stimulants, sedatives, or drug-adjacent agents are used
Botanical selection prioritizes human outcome data, not mechanistic hype
This layer enhances regulation only after foundational sufficiency is established

The separation of herbal signaling into AM and PM phases reflects biological timing, not marketing differentiation. This reduces risk, improves tolerability, and allows long-term daily use without escalation.

Relationship to Other Layers

Herbal Signaling Systems operate:

Downstream of:

🧬 Micronutrient Foundations
🦠 Microbiome Modulation

Upstream of:

⚙️ Structural & Functional Support
🧠 Cognitive aging and resilience outcomes

They do not compensate for deficiencies, nor do they force adaptation in unstable systems.

🧠 Omega-3 Essential Fatty Acids

Structural Lipids for Cellular Integrity and Lifelong Resilience

Omega-3 fatty acids are foundational structural components of human biology.
They are integral to cell membrane integrity, neurovascular signaling, inflammatory balance, mitochondrial efficiency, and long-term cardiovascular and cognitive health.

Within the NIMARSTI™ Health Architecture, omega-3s are not treated as optional “heart health” supplements or generalized anti-inflammatories. They are positioned as essential biological inputs that support membrane function, signaling fidelity, and adaptive capacity across the lifespan.

Role in the system
Provides essential lipid substrates required for cellular communication, neurodevelopment, vascular health, and resilience to aging-related decline.

Products Within This Layer

NIMARSTI™ Omega-3 Advanced™

Architectural Role
High-potency adult omega-3 system designed to support cardiovascular protection, cognitive health, inflammation resolution, and mitochondrial energy through therapeutic-grade EPA + DHA and CoQ10 synergy.

Lifecycle Context
Adult physiology.

Development Status
🔒 Formulation complete · Regulatory-ready · Architecture-locked
Planned for manufacturing following foundational system rollout.

NIMARSTI™ Kids Omega-3™

Architectural Role
Pediatric omega-3 foundation providing clean, algae-derived DHA to support brain development, vision, emotional regulation, and learning readiness without unnecessary lipid complexity.

Lifecycle Context
Pediatric (ages 4–12; adjusted dosing for ages 2–4 under guidance).

Development Status
🔒 Formulation complete · Regulatory-ready · Architecture-locked
Planned for later-stage release alongside pediatric micronutrient and microbiome foundations.

Architectural Notes (Investor-Relevant)

Adult and pediatric omega-3 needs are biologically distinct, not scaled versions
Adult formulation emphasizes EPA + DHA for cardiovascular and longevity outcomes
Pediatric formulation emphasizes DHA-only architecture for neurodevelopmental safety
Oxidation control and lipid integrity are treated as non-negotiable design constraints

Omega-3s are positioned as structural enablers, not performance enhancers, and are introduced only when upstream systems support proper absorption and utilization.

Relationship to Other Layers

Omega-3 Essential Fatty Acids operate within the broader NIMARSTI™ Health Architecture as a structural lipid layer.

Downstream of:
🧬 Micronutrient Foundations
🦠 Microbiome Modulation
🌿 Herbal Signaling Systems

Upstream of:
🧠 Cognitive aging, vascular resilience, and long-term cellular integrity outcomes

Omega-3 supplementation does not compensate for micronutrient insufficiency, digestive instability, or regulatory dysfunction. It reinforces cellular structure within a stable system.

⚙️ Developmental & Functional Support

Structural Capacity, Recovery, and Expression of Resilience

Developmental & Functional Support represents the layer where biological capacity is expressed—through tissue integrity, neuromuscular resilience, hydration, recovery, and age-appropriate physical capability.

Within the NIMARSTI™ Health Architecture, this layer does not initiate adaptation. It supports the expression of capacity that has already been established through foundational sufficiency, microbiome stability, and regulatory signaling.

This layer is deliberately conservative. It avoids stimulation, endocrine manipulation, and performance escalation in favor of structural integrity and long-term resilience.

Role in the system
Supports connective tissue integrity, cellular hydration, neuromuscular capacity, and developmental structure—without overriding regulation or accelerating biological demand.

Products Within This Layer

NIMARSTI™ Daily Optimize™

Architectural Role
Daily cellular and functional optimization formula designed to support hydration, recovery, connective tissue health, and metabolic resilience on both training and non-training days—without stimulants or performance forcing.

Lifecycle Context
Adult physiology.

Development Status
🔒 Formulation complete · OEM-ready · Regulatory-ready · Pilot-ready
Designed for daily use within a stable, regulated system.

NIMARSTI™ Structure™

Architectural Role
Structural protein and amino acid system designed to support connective tissue integrity, lean mass preservation, and hypertrophy-capable responsiveness when paired with appropriate training stimulus.

Lifecycle Context
Adult physiology.

Development Status
🔒 Formulation complete · OEM-ready · Regulatory-ready · Pilot-ready
Positioned for long-term tissue maintenance and age-related muscle preservation.

NIMARSTI™ Kids Formative™

Architectural Role
Pediatric developmental integrity support designed to provide structural substrates and calming cellular support during growth—without growth acceleration, endocrine signaling, or performance orientation.

Lifecycle Context
Pediatric (ages 4–12).

Development Status
🔒 Formulation complete · Architecture-locked
Designed for daily, long-term developmental support within the pediatric system.

Architectural Notes (Investor-Relevant)

This layer does not drive adaptation — it supports durability and recovery
Adult and pediatric formulations are explicitly separated
No stimulants, performance agents, or endocrine-active compounds are used
Structural substrates are favored over signaling escalation

Developmental & Functional Support is intentionally downstream. It becomes relevant only when biological regulation is intact, reducing misuse risk and improving long-term adherence.

Relationship to Other Layers

Developmental & Functional Support operates within the NIMARSTI™ Health Architecture as a capacity-expression layer.

Downstream of:
🧬 Micronutrient Foundations
🦠 Microbiome Modulation
🌿 Herbal Signaling Systems

Upstream of:
🧠 Physical resilience, mobility, and long-term functional independence outcomes

This layer does not compensate for deficiencies, dysregulation, or inadequate recovery capacity. It supports structural integrity within an already stable system.

A System Designed to Scale Without Fragmentation

The NIMARSTI™ Supplement Product Architecture is intentionally conservative in its rollout and expansive in its design.

Each formulation exists because the system requires it—not because a market opportunity demands it. This approach prioritizes long-term coherence, regulatory integrity, and biological safety over rapid SKU expansion.

By sequencing manufacturing according to biological dependency, NIMARSTI™ reduces misuse risk, improves tolerance, and creates a foundation for sustained adoption rather than short-term consumption. Products are introduced only when their upstream conditions are established and their role within the architecture is non-redundant.

From an operational perspective, this architecture supports disciplined growth:

Clear manufacturing prioritization without overextension
Modular expansion without reformulation or repositioning
Lifecycle-specific pathways that avoid product overlap
Long-term customer retention driven by system coherence, not escalation

From a biological perspective, it reflects how health actually functions—through structure, regulation, and cumulative resilience.

This is supplementation designed as infrastructure.

Not reactive.
Not trend-driven.
Not disposable.

As the architecture expands, its governing principles remain fixed. That stability is what allows the system—and the organization behind it—to scale without losing integrity.